Open access Short report In silico systems

A possible approach to computer simulation of the formation of platelet lamellipodia

Julia Korobkin¹

Julia Korobkin

1

Center For Theoretical Problems of Physico-Chemical Pharmacology RAS, 109029, Srednyaya Kalitnikovskaya 30, Moscow, Russia

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,

Anastasia Sveshnikova^1,2,3

Anastasia Sveshnikova

Anastasia Sveshnikova

MSU, Faculty of physics

Сorrespondence:[email protected]

1

Center For Theoretical Problems of Physico-Chemical Pharmacology RAS, 109029, Srednyaya Kalitnikovskaya 30, Moscow, Russia

2

Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology Immunology Ministry of Healthcare of Russian Federation, 117997, Samory Machela 1, Moscow Russia

3

Lomonosov Moscow State University, Physics Faculty 119991, Leninskiye Gory 1-2, Moscow, Russia

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1.

Center For Theoretical Problems of Physico-Chemical Pharmacology RAS, 109029, Srednyaya Kalitnikovskaya 30, Moscow, Russia

2.

Dmitriy Rogachev National Medical Research Center of Pediatric Hematology, Oncology Immunology Ministry of Healthcare of Russian Federation, 117997, Samory Machela 1, Moscow Russia

3.

Lomonosov Moscow State University, Physics Faculty 119991, Leninskiye Gory 1-2, Moscow, Russia

SBPReports; 2022; 63 (1), 9-12

DOI: 10.52455/sbpr.01.202263012

Received

December 1, 2022

Accepted

December 15, 2022

Published

December 29, 2022

Abstract

Dear editors of the journal System Biology and Physiology! In our previous article [1], a computer model of actin polymerization during the growth of neutrophil pseudopodium was proposed. In this letter, we propose a variant of using the same computer model to describe the growth of platelet lamellipodia.